Cargando…
Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes
The transcription factor E2F plays crucial roles in cell proliferation and tumor suppression by activating growth-related genes and pro-apoptotic tumor suppressor genes, respectively. It is generally accepted that E2F binds to target sequences with its heterodimeric partner DP. Here we show that, wh...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981219/ https://www.ncbi.nlm.nih.gov/pubmed/29855511 http://dx.doi.org/10.1038/s41598-018-26860-0 |