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Glutamate mediated metabolic neutralization mitigates propionate toxicity in intracellular Mycobacterium tuberculosis

Metabolic networks in biological systems are interconnected, such that malfunctioning parts can be corrected by other parts within the network, a process termed adaptive metabolism. Unlike Bacillus Calmette-Guérin (BCG), Mycobacterium tuberculosis (Mtb) better manages its intracellular lifestyle by...

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Detalles Bibliográficos
Autores principales: Lee, Jae Jin, Lim, Juhyeon, Gao, Shengjia, Lawson, Christopher P., Odell, Mark, Raheem, Saki, Woo, JeongIm, Kang, Sung-Ho, Kang, Shin-Seok, Jeon, Bo-Young, Eoh, Hyungjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981324/
https://www.ncbi.nlm.nih.gov/pubmed/29855554
http://dx.doi.org/10.1038/s41598-018-26950-z