Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513

Dengue is a widespread viral disease with 3.6 billion people at risk worldwide. Humanized monoclonal antibody (mAb) 513, currently undergoing clinical trials in Singapore, targets an epitope on the envelope protein domain III exposed at the surface of the viral particle. This antibody potently neutr...

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Detalles Bibliográficos
Autores principales: Wong, Yee Hwa, Kumar, Akshita, Liew, Chong Wai, Tharakaraman, Kannan, Srinivasaraghavan, Kannan, Sasisekharan, Ram, Verma, Chandra, Lescar, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981469/
https://www.ncbi.nlm.nih.gov/pubmed/29855525
http://dx.doi.org/10.1038/s41598-018-26800-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981469/
https://www.ncbi.nlm.nih.gov/pubmed/29855525
http://dx.doi.org/10.1038/s41598-018-26800-y

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