Fission Yeast Sirtuin Hst4 Functions in Preserving Genomic Integrity by Regulating Replisome Component Mcl1

The Schizosaccharomyces pombe sirtuin Hst4, functions in the maintenance of genome stability by regulating histone H3 lysine56 acetylation (H3K56ac) and promoting cell survival during replicative stress. However, its molecular function in DNA damage survival is unclear. Here, we show that hst4 defic...

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Detalles Bibliográficos
Autores principales: Konada, Lahiri, Aricthota, Shalini, Vadla, Raghavendra, Haldar, Devyani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981605/
https://www.ncbi.nlm.nih.gov/pubmed/29855479
http://dx.doi.org/10.1038/s41598-018-26476-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981605/
https://www.ncbi.nlm.nih.gov/pubmed/29855479
http://dx.doi.org/10.1038/s41598-018-26476-4

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