Chlamydia trachomatis-infected cells and uninfected-bystander cells exhibit diametrically opposed responses to interferon gamma

The intracellular bacterial pathogen, Chlamydia trachomatis, is a tryptophan auxotroph. Therefore, induction of the host tryptophan catabolizing enzyme, indoleamine-2,3-dioxgenase-1 (IDO1), by interferon gamma (IFNγ) is one of the primary protective responses against chlamydial infection. However, d...

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Detalles Bibliográficos
Autores principales: Ibana, Joyce A., Sherchand, Shardulendra P., Fontanilla, Francis L., Nagamatsu, Takeshi, Schust, Danny J., Quayle, Alison J., Aiyar, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981614/
https://www.ncbi.nlm.nih.gov/pubmed/29855501
http://dx.doi.org/10.1038/s41598-018-26765-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981614/
https://www.ncbi.nlm.nih.gov/pubmed/29855501
http://dx.doi.org/10.1038/s41598-018-26765-y

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