Cargando…

Disruption of the GDP-mannose synthesis pathway in Streptomyces coelicolor results in antibiotic hyper-susceptible phenotypes

Actinomycete bacteria use polyprenol phosphate mannose as a lipid linked sugar donor for extra-cytoplasmic glycosyl transferases that transfer mannose to cell envelope polymers, including glycoproteins and glycolipids. We showed recently that strains of Streptomyces coelicolor with mutations in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Howlett, Robert, Anttonen, Katri, Read, Nicholas, Smith, Margaret C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982138/
https://www.ncbi.nlm.nih.gov/pubmed/29493491
http://dx.doi.org/10.1099/mic.0.000636