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LUBAC and ABIN-1 Modulate TRAIL-Based NF-κB Induction in Human Embryonic Kidney 293 Cells

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is known to activate the canonical NF-κB pathway similar to TNF. The exact mechanism of the entire signaling cascade is still under investigation. The involvement of linear ubiquitylation as upregulating component has already been...

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Detalles Bibliográficos
Autores principales: Dorn, Sebastian, Schoergenhofer, Christian, Krainer, Michael, Müller, Markus, Jilma, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982153/
https://www.ncbi.nlm.nih.gov/pubmed/29862142
http://dx.doi.org/10.1089/biores.2018.0006