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A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system

Oligonucleotide probes that show enhanced fluorescence upon nucleic acid hybridization enable the detection and visualization of specific mRNA molecules, in vitro and in cellulo. A challenging problem is the analysis of single nucleotide alterations that occur, for example, when cellular mRNA is sub...

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Detalles Bibliográficos
Autores principales: Fang, Ge-min, Chamiolo, Jasmine, Kankowski, Svenja, Hövelmann, Felix, Friedrich, Dhana, Löwer, Alexander, Meier, Jochen C., Seitz, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982193/
https://www.ncbi.nlm.nih.gov/pubmed/29910930
http://dx.doi.org/10.1039/c8sc00457a