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A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system

Oligonucleotide probes that show enhanced fluorescence upon nucleic acid hybridization enable the detection and visualization of specific mRNA molecules, in vitro and in cellulo. A challenging problem is the analysis of single nucleotide alterations that occur, for example, when cellular mRNA is sub...

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Detalles Bibliográficos
Autores principales:	Fang, Ge-min, Chamiolo, Jasmine, Kankowski, Svenja, Hövelmann, Felix, Friedrich, Dhana, Löwer, Alexander, Meier, Jochen C., Seitz, Oliver
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982193/ https://www.ncbi.nlm.nih.gov/pubmed/29910930 http://dx.doi.org/10.1039/c8sc00457a

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