Protein scaffolded DNA tetrads enable efficient delivery and ultrasensitive imaging of miRNA through crosslinking hybridization chain reaction

Efficient intracellular delivery of nucleic acids to achieve sensitive detection and gene regulation is essential for chemistry and biology. Here we developed a novel protein scaffolded DNA tetrad, a four-arm DNA nanostructure constructed using streptavidin (SA) protein and four biotinylated hairpin...

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Detalles Bibliográficos
Autores principales: Huang, Du-Juan, Huang, Zhi-Mei, Xiao, Hu-Yan, Wu, Zhen-Kun, Tang, Li-Juan, Jiang, Jian-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982210/
https://www.ncbi.nlm.nih.gov/pubmed/29910942
http://dx.doi.org/10.1039/c8sc01001c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982210/
https://www.ncbi.nlm.nih.gov/pubmed/29910942
http://dx.doi.org/10.1039/c8sc01001c

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