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Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria
There is astounding discrepancy between the genome-inscribed production capacity and the set of known secondary metabolite classes from many microorganisms as detected under laboratory cultivation conditions. Genome-mining techniques are meant to fill this gap, but in order to favor discovery of str...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982219/ https://www.ncbi.nlm.nih.gov/pubmed/29910943 http://dx.doi.org/10.1039/c8sc01325j |