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Chimeric Antigen Receptor T-Cells (CAR T-Cells) for Cancer Immunotherapy – Moving Target for Industry?

The first CD19 CAR T-cell products, Kymriah and Yescarta, are entering the US market and also being evaluated for marketing authorization in the EU. This breakthrough has expanded the interest and also investments towards novel chimeric antigen receptor (CAR) designs, both for hematological malignan...

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Detalles Bibliográficos
Autores principales: Salmikangas, Paula, Kinsella, Niamh, Chamberlain, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982434/
https://www.ncbi.nlm.nih.gov/pubmed/29855723
http://dx.doi.org/10.1007/s11095-018-2436-z