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Pre-aggregation kinetics and intermediates of α-synuclein monitored by the ESIPT probe 7MFE

The defining feature of the extensive family of amyloid diseases is the formation of networks of entangled elongated protein fibrils and amorphous aggregates exhibiting crossed β-sheet secondary structure. The time course of amyloid conversion has been studied extensively in vitro with the proteins...

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Detalles Bibliográficos
Autores principales: Fauerbach, Jonathan A., Jovin, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982440/
https://www.ncbi.nlm.nih.gov/pubmed/29255947
http://dx.doi.org/10.1007/s00249-017-1272-0