A systematic analysis of the expression of the anti-HIV VRC01 antibody in Pichia pastoris through signal peptide optimization

Pichia pastoris (Komagataella phaffi) has been used for recombinant protein production for over 30 years with over 5000 proteins reported to date. However, yields of antibody are generally low. We have evaluated the effect of secretion signal peptides on the production of a broadly neutralizing anti...

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Detalles Bibliográficos
Autores principales: Aw, Rochelle, McKay, Paul F., Shattock, Robin J., Polizzi, Karen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982643/
https://www.ncbi.nlm.nih.gov/pubmed/29601964
http://dx.doi.org/10.1016/j.pep.2018.03.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982643/
https://www.ncbi.nlm.nih.gov/pubmed/29601964
http://dx.doi.org/10.1016/j.pep.2018.03.013

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