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The Janus Face of Follicular T Helper Cells in Chronic Viral Infections

Chronic infections with non-cytopathic viruses constitutively expose virus-specific adaptive immune cells to cognate antigen, requiring their numeric and functional adaptation. Virus-specific CD8 T cells are compromised by various means in their effector functions, collectively termed T cell exhaust...

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Detalles Bibliográficos
Autores principales: Greczmiel, Ute, Oxenius, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982684/
https://www.ncbi.nlm.nih.gov/pubmed/29887868
http://dx.doi.org/10.3389/fimmu.2018.01162