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Testing Pneumonia Vaccines in the Elderly: Determining a Case Definition for Pneumococcal Pneumonia in the Absence of a Gold Standard

Clinical assessments of vaccines to prevent pneumococcal community-acquired pneumonia (CAP) require sensitive and specific case definitions, but there is no gold standard diagnostic test. To develop a new case definition suitable for vaccine efficacy studies, we applied latent class analysis (LCA) t...

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Detalles Bibliográficos
Autores principales: Jokinen, Jukka, Snellman, Marja, Palmu, Arto A, Saukkoriipi, Annika, Verlant, Vincent, Pascal, Thierry, Devaster, Jeanne-Marie, Hausdorff, William P, Kilpi, Terhi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982705/
https://www.ncbi.nlm.nih.gov/pubmed/29253067
http://dx.doi.org/10.1093/aje/kwx373