Epigenetic reprogramming by naïve conditions establishes an irreversible state of partial X chromosome reactivation in female stem cells

Female human pluripotent stem cells (PSCs) have variable X-chromosome inactivation (XCI) status. One of the X chromosomes may either be inactive (Xi) or display some active state markers. Long-term cultivation of PSCs may lead to an erosion of XCI and partial X reactivation. Such heterogeneity and i...

Descripción completa

Detalles Bibliográficos
Autores principales: Panova, Alexandra V., Bogomazova, Alexandra N., Lagarkova, Maria A., Kiselev, Sergey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982739/
https://www.ncbi.nlm.nih.gov/pubmed/29861859
http://dx.doi.org/10.18632/oncotarget.25353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982739/
https://www.ncbi.nlm.nih.gov/pubmed/29861859
http://dx.doi.org/10.18632/oncotarget.25353

Ejemplares similares