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SNPs in predicting clinical efficacy and toxicity of chemotherapy: walking through the quicksand

In the “precision medicine” era, chemotherapy still remains the backbone for the treatment of many cancers, but no affordable predictors of response to the chemodrugs are available in clinical practice. Single nucleotide polymorphisms (SNPs) are gene sequence variations occurring in more than 1% of...

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Detalles Bibliográficos
Autores principales: Palmirotta, Raffaele, Carella, Claudia, Silvestris, Erica, Cives, Mauro, Stucci, Stefania Luigia, Tucci, Marco, Lovero, Domenica, Silvestris, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982750/
https://www.ncbi.nlm.nih.gov/pubmed/29861877
http://dx.doi.org/10.18632/oncotarget.25256