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FGFR signaling regulates resistance of head and neck cancer stem cells to cisplatin

Patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) have poor prognosis with less than 1-year median survival. Platinum-based chemotherapy remains the first-line treatment for HNSCC. The cancer stem cell (CSC) hypothesis postulates that tumors are maintained by a self...

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Detalles Bibliográficos
Autores principales: McDermott, Sarah C., Rodriguez-Ramirez, Christie, McDermott, Sean P., Wicha, Max S., Nör, Jacques E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982758/
https://www.ncbi.nlm.nih.gov/pubmed/29861860
http://dx.doi.org/10.18632/oncotarget.25358