Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells

Blood cells from patients with chronic lymphocytic leukemia (CLL) are replicationally quiescent but transcriptionally, translationally, and metabolically active. Recently, we demonstrated that oxidative phosphorylation (OxPhos) is a predominant pathway in CLL for energy production and is further aug...

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Detalles Bibliográficos
Autores principales: Vangapandu, Hima V., Alston, Brandon, Morse, Joshua, Ayres, Mary L., Wierda, William G., Keating, Michael J., Marszalek, Joseph R., Gandhi, Varsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982765/
https://www.ncbi.nlm.nih.gov/pubmed/29861847
http://dx.doi.org/10.18632/oncotarget.25166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982765/
https://www.ncbi.nlm.nih.gov/pubmed/29861847
http://dx.doi.org/10.18632/oncotarget.25166

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