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PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma

To better characterize the oncogenic role of the PAX3-FOXO1 fusion protein in the acquisition of aggressive behavior in ARMS, we employed a proteomic approach using a PAX3-FOXO1 knockdown system in ARMS cell lines. This approach revealed a protein list consisting of 107 consistently upregulated and...

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Detalles Bibliográficos
Autores principales: Akaike, Keisuke, Suehara, Yoshiyuki, Kohsaka, Shinji, Hayashi, Takuo, Tanabe, Yu, Kazuno, Saiko, Mukaihara, Kenta, Toda-Ishii, Midori, Kurihara, Taisei, Kim, Youngji, Okubo, Taketo, Hayashi, Yasuhide, Takamochi, Kazuya, Takahashi, Fumiyuki, Kaneko, Kazuo, Ladanyi, Marc, Saito, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982774/
https://www.ncbi.nlm.nih.gov/pubmed/29861864
http://dx.doi.org/10.18632/oncotarget.25392