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PPP2R1A regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma
To better characterize the oncogenic role of the PAX3-FOXO1 fusion protein in the acquisition of aggressive behavior in ARMS, we employed a proteomic approach using a PAX3-FOXO1 knockdown system in ARMS cell lines. This approach revealed a protein list consisting of 107 consistently upregulated and...
Autores principales: | Akaike, Keisuke, Suehara, Yoshiyuki, Kohsaka, Shinji, Hayashi, Takuo, Tanabe, Yu, Kazuno, Saiko, Mukaihara, Kenta, Toda-Ishii, Midori, Kurihara, Taisei, Kim, Youngji, Okubo, Taketo, Hayashi, Yasuhide, Takamochi, Kazuya, Takahashi, Fumiyuki, Kaneko, Kazuo, Ladanyi, Marc, Saito, Tsuyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982774/ https://www.ncbi.nlm.nih.gov/pubmed/29861864 http://dx.doi.org/10.18632/oncotarget.25392 |
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