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Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment

Glioma tumors constitute a significant portion of microglial cells, which are known to support tumor progression. The present study demonstrates that transforming growth factor-β (TGFβ) signaling pathway in microglia in a glioma environment is involved in tumor progression and pathogenesis. It has b...

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Detalles Bibliográficos
Autores principales: Karthikeyan, Aparna, Gupta, Neelima, Tang, Carol, Mallilankaraman, Karthik, Silambarasan, Maskomani, Shi, Meng, Lu, Lei, Ang, Beng Ti, Ling, Eng-Ang, Dheen, S. Thameem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982777/
https://www.ncbi.nlm.nih.gov/pubmed/29861845
http://dx.doi.org/10.18632/oncotarget.25116