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Multiple Arginine Residues Are Methylated in Drosophila Mre11 and Required for Survival Following Ionizing Radiation

Mre11 is a key player for DNA double strand break repair. Previous studies have shown that mammalian Mre11 is methylated at multiple arginines in its C-terminal Glycine-Arginine-Rich motif (GAR) by protein arginine methyltransferase PRMT1. Here, we found that the Drosophila Mre11 is methylated at ar...

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Detalles Bibliográficos
Autores principales: Yuan, Qing, Tian, Ran, Zhao, Haiying, Li, Lijuan, Bi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982836/
https://www.ncbi.nlm.nih.gov/pubmed/29695495
http://dx.doi.org/10.1534/g3.118.200298