Modeling transcriptional activation changes to Gal4 variants via structure-based computational mutagenesis

As a DNA binding transcriptional activator, Gal4 promotes the expression of genes responsible for galactose metabolism. The Gal4 protein from Saccharomyces cerevisiae (baker’s yeast) has become a model for studying eukaryotic transcriptional activation in general because its regulatory properties mi...

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Detalles Bibliográficos
Autores principales: Masso, Majid, Rao, Nitin, Pyarasani, Purnima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983003/
https://www.ncbi.nlm.nih.gov/pubmed/29868268
http://dx.doi.org/10.7717/peerj.4844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983003/
https://www.ncbi.nlm.nih.gov/pubmed/29868268
http://dx.doi.org/10.7717/peerj.4844

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