Secular changes in severity of intellectual disability in tuberous sclerosis complex: A reflection of improved identification and treatment of epileptic spasms?

Tuberous sclerosis complex (TSC) is a multisystem genetic disorder caused by mutations in TSC1 or TSC2. Epilepsy occurs in 80%‐90% of affected individuals during their lifetime, and up to one‐third of children with TSC will develop epileptic (infantile) spasms, for which vigabatrin has been shown to...

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Detalles Bibliográficos
Autores principales: Tye, Charlotte, Thomas, Laura E., Sampson, Julian R., Lewis, Julia, O'Callaghan, Finbar, Yates, John R. W., Bolton, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Short Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983114/
https://www.ncbi.nlm.nih.gov/pubmed/29881807
http://dx.doi.org/10.1002/epi4.12111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983114/
https://www.ncbi.nlm.nih.gov/pubmed/29881807
http://dx.doi.org/10.1002/epi4.12111

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