Cargando…
Mice lacking L‐12/15‐lipoxygenase show increased mortality during kindling despite demonstrating resistance to epileptogenesis
OBJECTIVE: Studies have addressed the potential involvement of L‐12/15‐lipoxygenases (LOs), a polyunsaturated fatty acid metabolizing enzyme, in experimental models of acute stroke and chronic neurodegeneration; however, none to our knowledge has explored its role in epilepsy development. Thus, this...
Autores principales: | Kanzler, Matthew A., Van Dyke, Adam M., He, Yan, Hewett, James A., Hewett, Sandra J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983117/ https://www.ncbi.nlm.nih.gov/pubmed/29881804 http://dx.doi.org/10.1002/epi4.12221 |
Ejemplares similares
-
Decreased epileptogenesis in mice lacking the System x(c)
(−) transporter occurs in association with a reduction in AMPA receptor subunit GluA1
por: Sears, Sheila M. S., et al.
Publicado: (2019) -
Hippocampal Expression of Connexin36 and Connexin43 during Epileptogenesis in Pilocarpine Model of Epilepsy
por: Motaghi, Sahel, et al.
Publicado: (2017) -
Low Frequency Electrical Stimulation Either Prior to Or after Rapid Kindling Stimulation Inhibits the Kindling-Induced Epileptogenesis
por: Jalilifar, Mostafa, et al.
Publicado: (2017) -
Blocking of rat hippocampal Cx36 by quinine accelerates kindling epileptogenesis
por: Ghanbarabadi, Jafar Kazemi, et al.
Publicado: (2013) -
The Spatiotemporal Dynamics of Phase Synchronization during Epileptogenesis in Amygdala-Kindling Mice
por: Li, Jia-Jia, et al.
Publicado: (2016)