The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E‐transformed cells

Metabolic reprogramming, as exemplified by the shift from oxidative phosphorylation to glycolysis, is a common feature of transformed cells. In many tumors, altered metabolism is also reflected in increased reactive oxygen species (ROS) levels, which contribute to proliferation and survival signalin...

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Detalles Bibliográficos
Autores principales: Furlan, Tobias, Khalid, Sana, Nguyen, Anh‐Vu, Günther, Julia, Troppmair, Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983121/
https://www.ncbi.nlm.nih.gov/pubmed/29624862
http://dx.doi.org/10.1002/1878-0261.12199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983121/
https://www.ncbi.nlm.nih.gov/pubmed/29624862
http://dx.doi.org/10.1002/1878-0261.12199

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