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The oxidoreductase p66Shc acts as tumor suppressor in BRAFV600E‐transformed cells
Metabolic reprogramming, as exemplified by the shift from oxidative phosphorylation to glycolysis, is a common feature of transformed cells. In many tumors, altered metabolism is also reflected in increased reactive oxygen species (ROS) levels, which contribute to proliferation and survival signalin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983121/ https://www.ncbi.nlm.nih.gov/pubmed/29624862 http://dx.doi.org/10.1002/1878-0261.12199 |