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Facilitation of kindling epileptogenesis by chronic stress may be mediated by intestinal microbiome

There has been growing interest in the role of intestinal microbiome in brain disorders. We examined whether dysbiosis can predispose to epilepsy. The study was performed in female and male Sprague‐Dawley rats. To induce dysbiosis, the rats were subjected to chronic restraint stress (two 2‐h long se...

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Detalles Bibliográficos
Autores principales: Medel‐Matus, Jesús‐Servando, Shin, Don, Dorfman, Edward, Sankar, Raman, Mazarati, Andrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983141/
https://www.ncbi.nlm.nih.gov/pubmed/29881810
http://dx.doi.org/10.1002/epi4.12114