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Exploiting Botulinum Neurotoxins for the Study of Brain Physiology and Pathology
Botulinum neurotoxins are metalloproteases that specifically cleave N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins in synaptic terminals, resulting in a potent inhibition of vesicle fusion and transmitter release. The family comprises different serotypes (BoNT/A to Bo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983231/ https://www.ncbi.nlm.nih.gov/pubmed/29693600 http://dx.doi.org/10.3390/toxins10050175 |