Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin

The Bordetella pertussis toxin (PT) is one important virulence factor causing the severe childhood disease whooping cough which still accounted for approximately 63,000 deaths worldwide in children in 2013. PT consists of PTS1, the enzymatically active (A) subunit and a non-covalently linked pentame...

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Detalles Bibliográficos
Autores principales: Ernst, Katharina, Eberhardt, Nina, Mittler, Ann-Katrin, Sonnabend, Michael, Anastasia, Anna, Freisinger, Simon, Schiene-Fischer, Cordelia, Malešević, Miroslav, Barth, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983237/
https://www.ncbi.nlm.nih.gov/pubmed/29723951
http://dx.doi.org/10.3390/toxins10050181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983237/
https://www.ncbi.nlm.nih.gov/pubmed/29723951
http://dx.doi.org/10.3390/toxins10050181

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