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The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model

The effector protein Exotoxin Y (ExoY) produced by Pseudomonas aeruginosa is injected via the type III secretion system (T3SS) into host cells. ExoY acts as nucleotidyl cyclase promoting the intracellular accumulation of cyclic nucleotides. To what extent nucleotidyl cyclase activity contributes to...

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Detalles Bibliográficos
Autores principales: Kloth, Christina, Schirmer, Bastian, Munder, Antje, Stelzer, Tane, Rothschuh, Justin, Seifert, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983241/
https://www.ncbi.nlm.nih.gov/pubmed/29734720
http://dx.doi.org/10.3390/toxins10050185