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The Role of Pseudomonas aeruginosa ExoY in an Acute Mouse Lung Infection Model
The effector protein Exotoxin Y (ExoY) produced by Pseudomonas aeruginosa is injected via the type III secretion system (T3SS) into host cells. ExoY acts as nucleotidyl cyclase promoting the intracellular accumulation of cyclic nucleotides. To what extent nucleotidyl cyclase activity contributes to...
Autores principales: | Kloth, Christina, Schirmer, Bastian, Munder, Antje, Stelzer, Tane, Rothschuh, Justin, Seifert, Roland |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983241/ https://www.ncbi.nlm.nih.gov/pubmed/29734720 http://dx.doi.org/10.3390/toxins10050185 |
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