Molecular Mechanisms of Apoptosis in HepaRG Cell Line Induced by Polyphyllin VI via the Fas Death Pathway and Mitochondrial-Dependent Pathway

Polyphyllin VI, which is an active saponin, is mainly isolated from traditional medicinal plant Paris polyphylla, which causes liver damage in rats. In the present study, we aimed to explore the potential cytotoxicity of polyphyllin VI on the growth of HepaRG cells and to determine the molecular mec...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Dong, Xiaoxv, Wang, Wenping, You, Longtai, Yin, Xingbin, Yang, Chunjing, Sai, Na, Leng, Xin, Ni, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983257/
https://www.ncbi.nlm.nih.gov/pubmed/29762502
http://dx.doi.org/10.3390/toxins10050201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983257/
https://www.ncbi.nlm.nih.gov/pubmed/29762502
http://dx.doi.org/10.3390/toxins10050201

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