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Haliotis discus discus Sialic Acid-Binding Lectin Reduces the Oncolytic Vaccinia Virus Induced Toxicity in a Glioblastoma Mouse Model

Although oncolytic viruses provide attractive vehicles for cancer treatment, their adverse effects are largely ignored. In this work, rat C6 glioblastoma cells were subcutaneously xenografted into mice, and a thymidine kinase-deficient oncolytic vaccinia virus (oncoVV) induced severe toxicity in thi...

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Detalles Bibliográficos
Autores principales: Li, Gongchu, Mei, Shengsheng, Cheng, Jianhong, Wu, Tao, Luo, Jingjing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983273/
https://www.ncbi.nlm.nih.gov/pubmed/29701680
http://dx.doi.org/10.3390/md16050141