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The Maxi-K (BK) Channel Antagonist Penitrem A as a Novel Breast Cancer-Targeted Therapeutic

Breast cancer (BC) is a heterogeneous disease with different molecular subtypes. The high conductance calcium-activated potassium channels (BK, Maxi-K channels) play an important role in the survival of some BC phenotypes, via membrane hyperpolarization and regulation of cell cycle. BK channels have...

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Detalles Bibliográficos
Autores principales: Goda, Amira A., Siddique, Abu Bakar, Mohyeldin, Mohamed, Ayoub, Nehad M., El Sayed, Khalid A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983288/
https://www.ncbi.nlm.nih.gov/pubmed/29751615
http://dx.doi.org/10.3390/md16050157