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Transient HIF2A inhibition promotes satellite cell proliferation and muscle regeneration

The remarkable regeneration capability of skeletal muscle depends on the coordinated proliferation and differentiation of satellite cells (SCs). The self-renewal of SCs is critical for long-term maintenance of muscle regeneration potential. Hypoxia profoundly affects the proliferation, differentiati...

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Detalles Bibliográficos
Autores principales: Xie, Liwei, Yin, Amelia, Nichenko, Anna S., Beedle, Aaron M., Call, Jarrod A., Yin, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983316/
https://www.ncbi.nlm.nih.gov/pubmed/29533927
http://dx.doi.org/10.1172/JCI96208