Regulation of mitochondrial trifunctional protein modulates nonalcoholic fatty liver disease in mice

Mitochondrial trifunctional protein (MTP) plays a critical role in the oxidation of long-chain fatty acids. We previously reported that aging mice (>9 months old) heterozygous for an MTP defect (MTP(+/−)) develop nonalcoholic fatty liver disease (NAFLD). We tested whether a high-fat diet (HFD) ac...

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Detalles Bibliográficos
Autores principales: Nassir, Fatiha, Arndt, Justin J., Johnson, Sarah A., Ibdah, Jamal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983392/
https://www.ncbi.nlm.nih.gov/pubmed/29581157
http://dx.doi.org/10.1194/jlr.M080952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983392/
https://www.ncbi.nlm.nih.gov/pubmed/29581157
http://dx.doi.org/10.1194/jlr.M080952

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