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Genome-wide screen reveals important roles for ESCRT proteins in drug/ion resistance of fission yeast

To study sodium homeostasis, we performed a genome-wide screen for deletion strains that show resistance to NaCl. We identified 34 NaCl-resistant strains. Among them, the largest group that consists of 10 genes related to membrane trafficking and 7 out of 10 genes are ESCRT proteins which are involv...

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Detalles Bibliográficos
Autores principales: Yang, Yikun, Liu, Qiannan, Jiang, Guanglie, Chen, Si, Zhou, Lina, Sakamoto, Norihiro, Kuno, Takayoshi, Fang, Yue, Yao, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983419/
https://www.ncbi.nlm.nih.gov/pubmed/29856841
http://dx.doi.org/10.1371/journal.pone.0198516