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In silico approaches for predicting the half-life of natural and modified peptides in blood

This paper describes a web server developed for designing therapeutic peptides with desired half-life in blood. In this study, we used 163 natural and 98 modified peptides whose half-life has been determined experimentally in mammalian blood, for developing in silico models. Firstly, models have bee...

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Detalles Bibliográficos
Autores principales: Mathur, Deepika, Singh, Sandeep, Mehta, Ayesha, Agrawal, Piyush, Raghava, Gajendra P. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983457/
https://www.ncbi.nlm.nih.gov/pubmed/29856745
http://dx.doi.org/10.1371/journal.pone.0196829