Circulating cell-free mitochondrial DNA, but not leukocyte mitochondrial DNA copy number, is elevated in major depressive disorder

Major depressive disorder (MDD) has been linked to mitochondrial defects, which could manifest in mitochondrial DNA (mtDNA) polymorphisms or mutations. Additionally, copy number of mtDNA (mtDNA-cn) can be quantified in peripheral blood mononuclear cells (PBMC)s, indirectly reflecting cellular energe...

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Detalles Bibliográficos
Autores principales: Lindqvist, Daniel, Wolkowitz, Owen M., Picard, Martin, Ohlsson, Lars, Bersani, Francesco S., Fernström, Johan, Westrin, Åsa, Hough, Christina M., Lin, Jue, Reus, Victor I., Epel, Elissa S., Mellon, Synthia H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983469/
https://www.ncbi.nlm.nih.gov/pubmed/29453441
http://dx.doi.org/10.1038/s41386-017-0001-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983469/
https://www.ncbi.nlm.nih.gov/pubmed/29453441
http://dx.doi.org/10.1038/s41386-017-0001-9

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