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Mathematical modelling of reversible transition between quiescence and proliferation

Cells switch between quiescence and proliferation states for maintaining tissue homeostasis and regeneration. At the restriction point (R-point), cells become irreversibly committed to the completion of the cell cycle independent of mitogen. The mechanism involving hyper-phosphorylation of retinobla...

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Detalles Bibliográficos
Autores principales: Pandey, Nishtha, Vinod, P. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983510/
https://www.ncbi.nlm.nih.gov/pubmed/29856829
http://dx.doi.org/10.1371/journal.pone.0198420