Impaired reward prediction error encoding and striatal-midbrain connectivity in depression

Anhedonia (hyposensitivity to rewards) and negative bias (hypersensitivity to punishments) are core features of major depressive disorder (MDD), which could stem from abnormal reinforcement learning. Emerging evidence highlights blunted reward learning and reward prediction error (RPE) signaling in...

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Detalles Bibliográficos
Autores principales: Kumar, Poornima, Goer, Franziska, Murray, Laura, Dillon, Daniel G., Beltzer, Miranda L., Cohen, Andrew L., Brooks, Nancy H., Pizzagalli, Diego A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983542/
https://www.ncbi.nlm.nih.gov/pubmed/29540863
http://dx.doi.org/10.1038/s41386-018-0032-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983542/
https://www.ncbi.nlm.nih.gov/pubmed/29540863
http://dx.doi.org/10.1038/s41386-018-0032-x

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