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Impaired reward prediction error encoding and striatal-midbrain connectivity in depression
Anhedonia (hyposensitivity to rewards) and negative bias (hypersensitivity to punishments) are core features of major depressive disorder (MDD), which could stem from abnormal reinforcement learning. Emerging evidence highlights blunted reward learning and reward prediction error (RPE) signaling in...
Autores principales: | Kumar, Poornima, Goer, Franziska, Murray, Laura, Dillon, Daniel G., Beltzer, Miranda L., Cohen, Andrew L., Brooks, Nancy H., Pizzagalli, Diego A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983542/ https://www.ncbi.nlm.nih.gov/pubmed/29540863 http://dx.doi.org/10.1038/s41386-018-0032-x |
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