A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse

Kappa opioid receptor (KOR) agonists have known anti-addiction properties and can reduce drug seeking. Their potential for clinical use has largely been daunted by their aversive properties mediated through p38 MAPK signaling. Here we examined the therapeutic potential of the KOR agonist U50,488 (U5...

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Detalles Bibliográficos
Autores principales: Heinsbroek, Jasper A., Furbish, Amelia B., Peters, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983548/
https://www.ncbi.nlm.nih.gov/pubmed/29472645
http://dx.doi.org/10.1038/s41386-017-0006-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983548/
https://www.ncbi.nlm.nih.gov/pubmed/29472645
http://dx.doi.org/10.1038/s41386-017-0006-4

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