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A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse
Kappa opioid receptor (KOR) agonists have known anti-addiction properties and can reduce drug seeking. Their potential for clinical use has largely been daunted by their aversive properties mediated through p38 MAPK signaling. Here we examined the therapeutic potential of the KOR agonist U50,488 (U5...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983548/ https://www.ncbi.nlm.nih.gov/pubmed/29472645 http://dx.doi.org/10.1038/s41386-017-0006-4 |