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Bone formation transcripts dominate the differential gene expression profile in an equine osteoporotic condition associated with pulmonary silicosis

Osteoporosis has been associated with pulmonary silicosis in California horses exposed to soils rich in cytotoxic silica dioxide crystals, a syndrome termed silicate associated osteoporosis (SAO). The causal mechanism for the development of osteoporosis is unknown. Osteoporotic lesions are primarily...

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Detalles Bibliográficos
Autores principales: Zavodovskaya, Regina, Stover, Susan M., Murphy, Brian G., Katzman, Scott, Durbin-Johnson, Blythe, Britton, Monica, Finno, Carrie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983561/
https://www.ncbi.nlm.nih.gov/pubmed/29856822
http://dx.doi.org/10.1371/journal.pone.0197459