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Variable termination sites of DNA polymerases encountering a DNA–protein cross-link

DNA-protein cross-links (DPCs) are important DNA lesions induced by endogenous crosslinking agents such as formaldehyde or acetaldehyde, as well as ionizing radiation, cancer chemotherapeutic drugs, and abortive action of some enzymes. Due to their very bulky nature, they are expected to interfere w...

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Detalles Bibliográficos
Autores principales: Yudkina, Anna V., Dvornikova, Antonina P., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983568/
https://www.ncbi.nlm.nih.gov/pubmed/29856874
http://dx.doi.org/10.1371/journal.pone.0198480