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Evaluation of different analysis pipelines for the detection of HIV-1 minority resistant variants

OBJECTIVE: Reliable detection of HIV minority resistant variants (MRVs) requires bioinformatics analysis with specific algorithms to obtain good quality alignments. The aim of this study was to analyze ultra-deep sequencing (UDS) data using different analysis pipelines. METHODS: HIV-1 protease, reve...

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Detalles Bibliográficos
Autores principales: Perrier, Marine, Désiré, Nathalie, Storto, Alexandre, Todesco, Eve, Rodriguez, Christophe, Bertine, Mélanie, Le Hingrat, Quentin, Visseaux, Benoit, Calvez, Vincent, Descamps, Diane, Marcelin, Anne-Geneviève, Charpentier, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983569/
https://www.ncbi.nlm.nih.gov/pubmed/29856864
http://dx.doi.org/10.1371/journal.pone.0198334